English Copy-Editors of Chinese Journal of Cancer
Dr. James R. Jabbur, Ph.D. Dr. Jheri Dupart, Ph.D.
Education
· Doctorate of Philosophy Molecular and Cellular Oncology, University of Texas Medical School and M.D. Anderson Cancer Center - Graduate School of Biomedical Sciences, Houston, Texas 2001
· Baccalaureate of Letters and Science Bacteriology (Microbiology), University of Wisconsin, Madison, Wisconsin, 1991
Teaching Experience
· Adjunct Biology Faculty, 2010 – Present
Houston Community College District
Courses: Introductory Biology
· Faculty, 2009 – Present
The Princeton Review of Houston
Courses: Hyperlearning MCAT and DAT preparatory courses
Professional, Technical, and Work-related Experience and Skills
· University of Texas – M.D. Anderson Cancer Center, Fellow Member of Academic and Hospital Staff, Houston, Texas, 1995 - 2003
· University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Laboratory Manager and Research Technician, Newark, New Jersey, 1992 - 1993
· Mount Sinai College of Medicine, Laboratory Manager and Research Technician, New York, New York, 1991-1992
· University of Wisconsin, Undergraduate Research Scholar and Laboratory Technician, Madison, Wisconsin 1989 - 1991
Professional Achievements and Honors
· American Legion Auxiliary Fellowship in Cancer Research (3 year appointment)
· AMGEN Award Fellowship in Cancer Research, University of Texas – M.D. Anderson Cancer Center
· University of Texas at Houston Graduate Project Award, Post-Candidacy Group
· Salk Institute of Biomedical Sciences Traveling Scholarship
· American Association of Cancer Research - AFLAC Traveling Scholarship
· President, University of Wisconsin at Madison Undergraduate Microbiology Society
Publications and Presentations
· Jabbur, J.R. A Doctoral Dissertation: Regulation of p53 Antiproliferative Function by Transactivation Domain Phosphorylation at Threonine 18 and Serine 20. University of Texas-MD Anderson Cancer Center, Graduate School of Biomedical Sciences, Department of Scientific Publications, Houston. 2003. 224 pages.
· Jabbur, J.R., Tabor, A.D., Cheng, X., Wang, H., Uesugi, M., Lozano, G. and Zhang, W. 2002. Mdm-2 Binding and TAFII31 Recruitment is Regulated by Hydrogen Bond Disruption between the p53 Residues Threonine 18 and Aspartate 21. Oncogene 21, 7100-7113.
· Jabbur, J.R. and Zhang, W. 2002. p53 Antiproliferative Function is Enhanced by Aspartate Substitution at Threonine 18 and Serine 20. Cancer Biol. Ther. 1, 277-283.
· Jabbur, J.R., Huang, P. and Zhang, W. 2001. Enhancement of the Antiproliferative Function of p53 by Phosphorylation at Serine 20: an Inference from Site-Directed Mutagenesis Studies. Int. J. Mol. Med. 7, 163-168.
· Jabbur, J.R., Huang, P. and Zhang, W. 2000. DNA Damage-Induced Phosphorylation of p53 at Serine 20 Correlates with p21 and Mdm-2 Induction in vivo. Oncogene 19, 6203-6209.
· Wang, H., Jabbur, J.R. and Zhang, W. The Effect of Phosphorylation of Threonine 18 on p53 Transactivation Function. Proceedings of the MD Anderson Cancer Center Symposia on Cancer Research. Volume 51, Page 124, January 2000. The University of Texas-MD Anderson Cancer Center, Department of Scientific Publications, Houston.
· Rhee, C.H., Hess, K., Jabbur, J.R., Ruiz, M., Yang, Y., Chen, S., Chenchik, A., Fuller, G.N. and Zhang, W. 1999. cDNA Expression Array Reveals Heterogeneous Gene Expression Profiles in three Glioblastoma Cell Lines. Oncogene 18, 2711-2707.
· Kobayashi, T., Ruan, S.-B., Jabbur, J.R., Consoli, U., Clodi, K., Shiku, H., Owen-Schaub, L., Andreeff, M., Reed, J.C. and Zhang, W. 1998. Differential p53 Phosphorylation and Activation of Apoptosis-Promoting Genes Bax and Fas/Apo-1 by Radiation and Ara-C Treatment. Cell Death and Differ. 5, 584-591.
· Jabbur, J.R. A Laboratory Manual: An Introductory Laboratory Course in Molecular Biology. Seton Hall University Press. 1993. 174 pages.
Education and Experience
· Doctorate of Philosophy Biomedical Science, University of Texas Health Science Center at Houston.
· Personal experience writing and editing manuscripts for peer-reviewed journals
· professional experience editing grants for submission to national and international funding agencies
Publications
· Dupart JJ, Trent JC, Lee H-Y, Hess KR, Godwin AK, Taguchi T, and Zhang W. Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro. Mol Cancer (2009) 8: 99.
· Trent JC, Ramdas L, Dupart JJ, Hunt K, Macapinlac H, Taylor EE, Hu L, Salvado A, Abbruzzese JL, Pollock R, Benjamin RS, and Zhang W. Early effects of imatinib mesylate on the expression of insulin-like growth factor binding protein-3 and positron emission tomography in patients with gastrointestinal stromal tumor. Cancer (2006) 107: 1898-1908.
· Trent JC, Dupart J, and Zhang W. Imatinib mesylate: targeted therapy of gastrointestinal stromal tumor. Current Cancer Therapy Reviews (2005) 1: 93-108.
· Choi W, Gerner EW, Ramdas L, Dupart J, Carew J, Proctor L, Huang P, Zhang W, Hamilton SR. Combination of 5-fluorouracil and N1, N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase SSAT expression, depletes polyamines, and synergistically induces apoptosis in colon cancer cells. J Biol Chem (2005) 280: 3295-3304.








