Lectures are 20 minutes long followed by 10 minutes discussion.

Day 1

Friday May 11, 2018

08:30 – 08:45

Prof. Qian (Miles) Chao-Nan

Sun Yat-sen University Cancer Center, China


Prof. Francesco Pezzella

John Radcliffe Hospital, University of Oxford, UK


Welcome and opening remarks

08:45 – 09:00

Speaker group photo

Biology Session

Session Chair: Prof. Bruno Péault


09:00 – 09:30

Alia Komsany

Radcliffe Department of Medicine, University of Oxford, UK


Discovery of molecular signatures underlying angiogenic versus non angiogenic metastatic cancer cells

09:30 – 10:00

Prof. Yihai Cao

Karolinska Institute, Sweden


Mechanistic insights on antiangiogenic cancer therapy

10:00 – 10:30

Prof. Baohui Han

Shanghai Chest Hospital, Shanghai Jiao Tong University, China


Anlotinib as third-line treatment in patients with refractory advanced non-small cell lung cancer: a multicenter, randomized, double-blind, placebo-controlled, phase III trial



Refreshment break 10:30-10:45


Session Chair: Alia Komsany

10:45 – 11:15

Prof. Guoquan Gao

Zhongshan School of Medicine, Sun Yat-Sen University, China


Effects and mechanism of endogenous inhibitors on cancer angiogenesis and lymphangiogenesis

11:15 - 11:45

Dr. Tingting Qin

Tianjin Medical University Cancer Institute and Hospital, China


Bevacizumab promotes the migration and tube-formation of endothelial cells via up-regulating CD105 expression and activating TGFbeta1 signaling

11:45 – 12:15

Prof. Bruno Péault

UCLA/Orthopaedic Surgery, Orthopaedic Hospital Research Center, USA


Perivascular cells in tissue scarring, regeneration and malignancy: friends or foes


Lunch 12:15 – 13:45



Metastatic Disease

Session Chair: Dr. Claire Lugassy



13:45 – 14:15


Manuel Valiente, PhD

Brain Metastasis Group at CNIO, Spain


Vascular co-option in brain metastasis: molecular mediators and functional implications

14:15 – 14:45

Prof. Raymond L. Barnhill

Institut Curie, and the Faculty of Medicine, University of Paris Descartes, France


Histopathologic Growth Patterns in Hepatic Metastases from Uveal Melanoma: A Study of 41 Cases


Refreshment Break 14:45-15:00



Session Chair: Manuel Valiente, PhD


15:00 – 15:30

Prof. Chao-Nan (Miles) Qian

Sun Yat-sen University Cancer Center, China


Vessel co-option in sentinel lymph node and its relationship with distant metastasis

15:30 – 16:00

Dr. Claire Lugassy

Institut Curie Research Center, France


Intravascular and Extravascular cancer cell migration and metastasis: Historical Critique and New Observations

Day 2

Saturday May 12, 2018

08:45 – 09:00

Pre-meeting video show:  SYSUCC introduction


Metastatic Disease Continued

Session Chair: Dr. Jackeline Agorreta Arrazubi


09:00 – 09:30

Prof. Shi-Mei Zhuang

School of Life Sciences, Sun Yat-set University, China


VETC: A novel vascular pattern that promotes metastasis of hepatocellular carcinoma in an EMT-independent manner


Treatment Strategies




09:30 – 10:00

Prof. Robert S. Kerbel

Biological Sciences Platform, Sunnybrook Research Institute, Dept. of Medical Biophysics, University of Toronto, Canada


Anti-vascular strategies under development to target co-opted tumor blood vessels in metastases



10:00 – 10:30

Prof. Raffaella Giavazzi

Mario Negri Institute for Pharmacological Research, Italy


Choice of therapy regimens to accompany antiangiogenic treatments


Refreshment Break 10:30-10:45


Session Chair: Prof. Robert S. Kerbel




10:45 – 11:15

Karl Morten, PhD

Nuffield Department of Women’s & Reproductive Health, Medical Sciences Division, University of Oxford, UK


Targeting cancer cell metabolism and better modelling the in vivo environment (under revision)



11:15 - 11:45

Dr. Jackeline Agorreta Arrazubi

Center of Applied Medical Research (CIMA), University of Navarra, Spain


Effects of targeted therapies and immunotherapy on lung cancer blood vessels



11:45 – 12:15

Dr. Giorgio Seano

Institut Curie Research Center, France


Vessel co-option in glioblastoma: spy it, find the target and shoot


Lunch 12:15 – 13:15


Session Chair: Prof. Francesco Pezzella


13:15 – 13:45


Dr. Jianting Hu

Radcliffe Department of Medicine, University of Oxford, UK


The role of TRAP1 in Neoplastic Angiogenesis

13:45 – 14:15

Kabir A. Khan, PhD

Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Canada


The interplay between tumour immunity and the tumour vasculature


Refreshment Break 14:15-14:30


14:30 – 15:00

Steve Yu, PhD

Director of Custom Animal Models and Chief Scientist at Cyagen Biosciences, Inc. China


The humanized mouse models for cancer research

15:00 –15:30

Prof. Francesco Pezzella & Prof. Qian (Miles) Chao-Nan

John Radcliffe Hospital, University of Oxford, UK

Sun Yat-sen University Cancer Center, China


General discussion and closing remarks












  The 4th International Meeting on Cancer and Blood Vessels