doi: 10.1186/s40880-015-0059-x
Differentiation therapy: a promising strategy for cancer treatment
Min Yan and Quentin Liu
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center
[Abstract] Poor differentiation is an important hallmark of cancer cells, and differentiation therapy holds great promise for cancer treatment. The restoration of IkB kinase α (IKKα) leads to the differentiation of nasopharyngeal carcinoma cells with reduced tumorigenicity. The findings by Yan et al. validate the polycomb protein enhancer of zeste homologue 2 (EZH2) as a target for intervention.
Chinese Journal of Cancer 2016, Volume: 35, Issue 1
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Min Yan and Quentin Liu. Differentiation therapy: a promising strategy for cancer treatment. Chin J Cancer. 2016, 35:3. doi:10.1186/s40880-015-0059-x
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[ Html full-text / Citation export] (BioMed Central)
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Min Yan and Quentin Liu. Differentiation therapy: a promising strategy for cancer treatment. Chin J Cancer. 2016, 35:3. doi:10.1186/s40880-015-0059-x
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