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Volume:36 Issue:6   2017

Mature T-cell and natural killer (NK)-cell lymphomas compose a heterogeneous group of non-Hodgkin lymphomas, and extranodal NK/T-cell lymphoma, nasal type (ENKTL) is an aggressive subtype with sporadic CD30 expression. However, the significance of CD30 expression in ENKTL is controversial. The cover art shows the immunohistochemical (IHC) and in situ hybridization (ISH) staining of ENKTL. a, Tumor cells show strong membranous and cytoplasmic expression of CD56. b, Tumor cells show strong nuclear expression of Epstein-Barr virus (EBV)-encoded small RNA. c, Tumor cells show strong diffuse membranous and Golgi zone expression of CD30. For more details, please read the paper on pages 258-266 of the present CJC issue. (The cover art is provided by Yanfen Feng and colleagues.)




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