Chinese Journal of Cancerindexed by SCI
《癌症》杂志
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Professor Chao-Nan Qian


AFFILIATIONS
Laboratory of Cancer and Developmental Cell Biology
Van Andel Research Institute
333 Bostwick Ave NE
Grand Rapids, Michigan 49503, USA.
Email: chaonan.qian@vai.org

Department of Nasopharyngeal Carcinoma
State Key Laboratory of Oncology in South China
Sun Yat-sen University Cancer Center
651 Dongfeng East Rd, Guangzhou 510060, P. R. China.
Email: qianchn@sysucc.org.cn
 
 

EDUCATION

1992 Sun Yat-sen University of Medical Sciences, Guangzhou, P.R. China, Bachelor in Medicine.

1999 Sun Yat-sen University of Medical Sciences, Guangzhou, P.R. China, Ph.D. (Oncology)


RESIDENCY TRAINING

1992 – 1994 The First Affiliated Hospital and The Cancer Center, Sun Yat-sen University of Medical Sciences.


POSTDOCTORAL TRAINING

Feb 2000 – Nov 2000 University of Texas MD Anderson Cancer Center, Houston, TX.

Nov 2000 – Jan 2003 Van Andel Research Institute, Grand Rapids, Michigan.


SELECTED PUBLICATIONS (from >70 papers)

1. Cao Y, Zhang ZL, Zhou M, Elson P, Rini B, Aydin H, Feenstra K, Tan MH, Berghuis B, Tabbey R, Resau JH, Zhou FJ, Teh BT, Qian CN. Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma. Cancer 2012 Jul 18. doi: 10.1002/cncr.27746. [Epub ahead of print]
2. Li XJ, Peng LX, Shao JY, Lu WH, Zhang JX, Chen S, Chen ZY, Xiang YQ, Bao YN, Zheng FJ, Zeng MS, Kang TB, Zeng YX, Teh BT, Qian CN. As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial-mesenchymal transition and activation of AKT signaling. Carcinogenesis 2012; 33(7): 1302-1309.
3. Ong CK, Subimerb C, Pairojkul C, Wongkham S, Cutcutache I, Yu W, McPherson JR, Allen GE, Ng CC, Wong BH, Myint SS, Rajasegaran V, Heng HL, Gan A, Zang ZJ, Wu Y, Wu J, Lee MH, Huang D, Ong P, Chan-On W, Cao Y, Qian CN, Lim KH, Ooi A, Dykema K, Furge K, Kukongviriyapan V, Sripa B, Wongkham C, Yongvanit P, Futreal PA, Bhudhisawasdi V, Rozen S, Tan P, Teh BT. Exome sequencing of liver fluke-associated cholangiocarcinoma. Nature Genetics 2012; 44(6):690-693.
4. Qin L, Bromberg-White JL, Qian CN. Opportunities and challenges in tumor angiogenesis research: back and forth between bench and bed. Advances in Cancer Research 2012; 113:191-239
5. Li GP, Wang H, Lai YK, Chen SC, Lin MC, Lu G, Zhang JF, He XG, Qian CN, Kung HF. Proteomic profiling between CNE-2 and its strongly metastatic subclone S-18 and functional characterization of HSP27 in metastasis of nasopharyngeal carcinoma. Proteomics 2011; 11(14): 2911-20.
6. Li XJ, Ong CK, Cao Y, Xiang Y, Shao JY, Ooi A, Peng LX, Lu WH, Zhang Z, Petillo D, Qin L, Bao YN, Zheng FJ, Chia CS, Iyer NG, Kang TB, Zeng YX, Soo KC, Trent JM, Teh BT, Qian CN. Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis. Cancer Res 2011; 71(8): 3162-3172.
7. Qian CN. Exploration of the postponing mechanism that delays carcinoma onset. Cancer Cell International 2010; 10: 38.
8. Wee JT, Ha TC, Loong SL, Qian CN. Is nasopharyngeal cancer really a "Cantonese cancer"? Chinese Journal of Cancer 2010; 29(5):517-26.
9. Wee JT, Anderson BO, Corry J, D’Cruz A, Soo KC, Qian CN, Chua DT, Hicks RJ, Goh HK, Khoo JB, Ong SC, Forastiere AA, Chan AT. Management of the neck following chemo-radiotherapy for head and neck cancers. Consensus statement from the Asian Oncology Summit 2009. Lancet Oncology 2009; 10(11): 1086-1092.
10. Qian CN, Furge K, Knol J, Huang D, Chen J, Dykema KJ, Kort EJ, Massie A, Khoo SK, VandenBeldt K, Resau JH, Anema J, Kahnoski RJ, Morreau H, Camparo P, Comperat E, Sibony M, Denoux Y, Molinie V, Vieillefond A, Eng C, Williams BO, Teh BT. Activation of the PI3K/AKT pathway induces transitional cell carcinoma of the renal pelvis: Identification in human tumors and confirmation in animal models. Cancer Research 2009; 69(21): 8256-8264.
11. Qian CN, Huang D, Wondergem B, Teh BT. Complexity of tumor vasculature in clear cell renal cell carcinoma. Cancer 2009; 115(10 Suppl): 2282-2289.
12. Huang D, Ding Y, Zhou M, Rini BI, Petillo D, Qian CN, Kahnoski R, Futreal PA, Furge KA, Teh BT. Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Research 2010; 70(3):1063-71.
13. Huang D, Ding Y, Luo WM, Bender S, Qian CN, Kort EJ, Zhang CF, VandenBeldt K, Duesbery N, Resau JH, Teh BT. Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo. Cancer Research 2008; 68(1): 81-88.
14. Qian CN, Resau JH, Teh BT. Prospects for vasculature reorganization in sentinel lymph nodes. Cell Cycle 2007; 6(5):514-517.
15. Yao X, Qian CN, Zhang ZF, Tan MH, Kort EJ, Yang XJ, Resau JH, Teh BT. Two distinct types of blood vessels in clear cell renal cell carcinoma have contrasting prognostic implications. Clinical Cancer Research 2007; 13(1):161-169.
16. Qian CN, Berghuis B, Tsarfaty G, Bruch M, Kort EJ, Ditlev J, Tsarfaty I, Hudson E, Jackson DG, Petillo D, Chen J, Resau JH, Teh BT. Preparing the "Soil": The Primary Tumor Induces Vasculature Reorganization in the Sentinel Lymph Node before the Arrival of Metastatic Cancer Cells. Cancer Research 2006; 66(21):10365-10376.
17. Qian CN, Knol J, Igarashi P, Lin F, Zylstra U, Teh BT, Williams BO. Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium. The Journal of Biological Chemistry 2005; 280(5):3938-3945.
18. Qian CN, Guo X, Cao B, Kort EJ, Lee CC, Chen, Wang LM, Mai WY, Min HQ, Hong MH, Vande Woude GF, Resau JH, Teh BT. Met protein expression level correlates with survival in patients with late-stage nasopharyngeal carcinoma. Cancer Research 2002; 62(2): 589-596.
19. Shi Q, Le X, Abbruzzese JL, Peng Z, Qian CN, Tang H, Xiong Q, Wang B, Li XC, Xie K. Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma. Cancer Research 2001; 61(10): 4143-4154.
20. Qian CN, Zhang CQ, Guo X, Hong MH, Cao SM, Mai WY, Min HQ, Zeng YX. Elevation of serum vascular endothelial growth factor in male patients with metastatic nasopharyngeal carcinoma. Cancer 2000; 88(2): 255-261.
 

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